Polymorphous Low‐Grade Adenocarcinoma

Objective We present a series of 18 cases of polymorphous low‐grade adenocarcinoma. Method We retrospectively reviewed all documented cases of polymorphous low‐grade adenocarcinoma at our institution since 1984. Each case was confirmed by pathologic examination. Results The median age of this series is 59 years. Eleven out of the 18 patients were female and 13 were white. Fifteen of the tumors were located on the hard/soft palate. Nearly every patient was treated with wide local excision, and 8 required reconstruction with flaps. Only 3 patients were treated with postoperative radiation. 4 patients were treated for recurrences, 2 of which were originally treated 20 years prior. Conclusion Polymorphous low‐grade adenocarcinoma is a rare and slow growing entity. Surgical excision is the treatment of choice and radiation therapy is generally not needed. Long term follow‐up is required, as recurrences have been noted after long periods of time. Differentiation from adenoid cystic carcinoma can be difficult.