Open AccessEffects of Surface Dehydration on Mucosal Wave Amplitude and Frequency in Excised Canine Larynges
Author(s) -
Witt Rachel E.,
Taylor Lindsay N.,
Regner Michael F.,
Jiang Jack J.
Publication year - 2011
Publication title -
otolaryngology–head and neck surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.232
H-Index - 121
eISSN - 1097-6817
pISSN - 0194-5998
DOI - 10.1177/0194599810390893
Subject(s) - phonation , dehydration , larynx , amplitude , medicine , materials science , biomedical engineering , anatomy , chemistry , audiology , optics , physics , biochemistry
Objective Evaluate the effect of vocal fold surface dehydration on mucosal wave amplitude and frequency. Study Design Controlled test‐retest. Setting Larynges were mounted on an excised larynx phonation system and attached to a pseudolung in a triple‐walled sound‐attenuated room that eliminated background noise and maintained a stabilized room temperature and humidity level. Subjects and Methods High‐speed video was recorded for 8 excised canine larynges during exposure to dehumidified air at 20 cm H 2 O. Control trials consisted of high‐speed videos recorded for 2 excised canine larynges during exposure to humidified air at the same pressure. Results In the majority of larynges, increased levels of dehydration were correlated with decreased amplitude and frequency. The slope of the linear regression fitted to the change in amplitude ( P =. 003) and the percent change ( P <. 001) between the initial and final trials were significantly decreased in dehydrated larynges. These measurements with respect to the change in frequency were also significantly decreased in dehydrated larynges ( P <. 001; P =. 027). Conclusion Vocal fold surface dehydration caused a decrease in mucosal wave amplitude and frequency. This study provides objective, quantitative support for the mechanism of voice deterioration observed after extreme surface dehydration.