A Pilot Study of the Effect upon Multiple Sclerosis of the Menopause, Hormone Replacement Therapy and the Menstrual Cycle | Zendy

Roger Smith | Zendy; J. W. W. Studd | Zendy

Open Access

A Pilot Study of the Effect upon Multiple Sclerosis of the Menopause, Hormone Replacement Therapy and the Menstrual Cycle

Author(s) -

Roger Smith,

J. W. W. Studd

Publication year - 1992

Publication title -

journal of the royal society of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.38

H-Index - 81

eISSN - 1758-1095

pISSN - 0141-0768

DOI - 10.1177/014107689208501008

Subject(s) - menopause , medicine , menstrual cycle , hormone replacement therapy (female to male) , multiple sclerosis , hormone therapy , menstruation , estrogen replacement therapy , gynecology , hormone , physical therapy , breast cancer , cancer , testosterone (patch) , psychiatry

A questionnaire enquiring about changes in severity of symptoms of multiple sclerosis with the menstrual cycle, menopause and use of hormone replacement therapy was answered retrospectively by 11 premenopausal and 19 postmenopausal women. Eighty-two per cent of menopausal women reported an increase in severity premenstrually. Of the postmenopausal women 54% reported a worsening of symptoms with the menopause, and 75% of those who had tried hormone replacement therapy reported an improvement. The results of this pilot study indicate the need for further research to clarify the effects of the menopause and hormone replacement therapy upon multiple sclerosis.

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