Open AccessAtlantoaxial Instability in down Syndrome-Guidelines for Screening and Detection
Author(s) -
Roy M,
Mike Baxter,
Roy A
Publication year - 1990
Publication title -
journal of the royal society of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.38
H-Index - 81
eISSN - 1758-1095
pISSN - 0141-0768
DOI - 10.1177/014107689008300708
Subject(s) - atlantoaxial instability , radiological weapon , medicine , down syndrome , pediatrics , chi square test , surgery , psychiatry , cervical spine , statistics , mathematics
A community survey was conducted in all adults with Down syndrome living in three health districts to see if there was any correlation between radiological and neurological abnormalities which could indicate the presence of atlantoaxial instability. There was no difference in the proportion of individuals with neurological abnormalities in the group with radiological abnormalities suggestive of atlantoaxial instability (6/14) compared with individuals with normal X-rays (50/123) as determined by the chi square test (0.01463: not significant). The clinical and ethical implications for screening of people with Down syndrome living in the community are discussed in view of these findings.