Placental Angiogenic and Growth Factors in the Treatment of Chronic Varicose Ulcers: Preliminary Communication | Zendy

Hugo Burgos | Zendy; Andrew Herd | Zendy; J.P. Bennett | Zendy

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Placental Angiogenic and Growth Factors in the Treatment of Chronic Varicose Ulcers: Preliminary Communication

Author(s) -

Hugo Burgos,

Andrew Herd,

J.P. Bennett

Publication year - 1989

Publication title -

journal of the royal society of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.38

H-Index - 81

eISSN - 1758-1095

pISSN - 0141-0768

DOI - 10.1177/014107688908201011

Subject(s) - granulation tissue , medicine , varicose veins , placenta , wound healing , surgery , pathology , biology , pregnancy , fetus , genetics

A short-term clinical study on the effect of purified angiogenic and growth factors from human term placenta in the treatment of chronic varicose ulcers was carried out in 18 patients. Patients were randomly allocated to receive a maximum of two dressings containing or not containing these factors. The amount of granulation and epithelial tissue was clinically estimated 48 hours after each application. Patients treated with placental angiogenic and growth factors showed increased granulation and epithelial tissue. These results indicate that placental factors may be used for acceleration of wound healing.

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