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Carcinoma of the Colon — Association with Low Dietary Vitamin A in Females: Preliminary Communication
Author(s) -
G.H. Tomkin,
Louise Scott,
Christopher Ogbuah,
M. T. O'Shaughnessy
Publication year - 1986
Publication title -
journal of the royal society of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.38
H-Index - 81
eISSN - 1758-1095
pISSN - 0141-0768
DOI - 10.1177/014107688607900810
Subject(s) - colorectal cancer , medicine , vitamin , carcinoma , cholesterol , feces , endocrinology , excretion , cancer , retinol , bile acid , gastroenterology , physiology , biology , paleontology
Seventeen patients with non-metastatic carcinoma of the colon (9 male, 8 female) were compared with age- and sex-matched controls in a study examining the relationship of diet and altered cholesterol metabolism with carcinoma of the colon. Bile acid excretion in the faeces was significantly less in cancer patients ( P > 0.001), and a significantly lower intake of retinol ( P > 0.01) and vitamin A ( P > 0.05) was demonstrated in female cancer patients. There was no difference between patients and controls in hepatic cholesterol enzyme activity or in fasting plasma lipid levels.

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