Relationship between Retinopathy and Glycaemic Control in Insulin-Dependent and Non-Insulin-Dependent Diabetes
Author(s) -
JP Monson,
G Koios,
G.C. Toms,
Peter Kopelman,
Barbara J. Boucher,
Stephen Evans,
Wressnegger Alexander
Publication year - 1986
Publication title -
journal of the royal society of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.38
H-Index - 81
eISSN - 1758-1095
pISSN - 0141-0768
DOI - 10.1177/014107688607900506
Subject(s) - medicine , diabetes mellitus , retinopathy , diabetic retinopathy , insulin , logistic regression , population , endocrinology , metabolic control analysis , environmental health
The possible relationship between antecedent diabetic control, as determined by serial glycosylated haemoglobin (HbA 1 ) measurements, and diabetic retinopathy was examined in 40 insulin-dependent and 41 non-insulin-dependent diabetics selected consecutively from our clinic population. Multiple logistic regression analysis demonstrated a significant association between mean HbA 1 and prevalence of retinopathy in both groups of patients. This association was independent of duration of diabetes which was also significantly associated with retinopathy prevalence. Hypertension and smoking were not obvious risk factors in this group of patients; an apparent association of hypertension and diabetes was entirely accounted for by a positive relationship between the presence of hypertension and duration of diabetes.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom