Open AccessAtropine or Glycopyrrolate with Neostigmine 5 mg: A Comparative Dose-Response Study
Author(s) -
M.G. Salem,
R.S. Ahearn
Publication year - 1986
Publication title -
journal of the royal society of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.38
H-Index - 81
eISSN - 1758-1095
pISSN - 0141-0768
DOI - 10.1177/014107688607900107
Subject(s) - glycopyrrolate , neostigmine , atropine , anesthesia , medicine
One hundred and fifteen patients, separated into 4 groups, received neostigmine 5 mg with either atropine 1.2 mg or 1.8 mg, or glycopyrrolate 0.6 mg or 0.9 mg. Those receiving 0.9 mg glycopyrrolate had insignificant changes in heart rate in the immediate postreversal period. It is recommended that when glycopyrrolate is used with 5 mg neostigmine, the optimum dose is 0.9 mg.
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