Tympanic Epithelium: An Ultrastructural, Experimental and Clinical Study | Zendy

Gerard M. O’Donoghue | Zendy

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Tympanic Epithelium: An Ultrastructural, Experimental and Clinical Study

Author(s) -

Gerard M. O’Donoghue

Publication year - 1984

Publication title -

journal of the royal society of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.38

H-Index - 81

eISSN - 1758-1095

pISSN - 0141-0768

DOI - 10.1177/014107688407700910

Subject(s) - tympan , guinea pig , ultrastructure , tympanum (architecture) , epithelium , anatomy , perforation , middle ear , effusion , pathology , staining , membrane , medicine , biology , surgery , materials science , tympanosclerosis , biochemistry , metallurgy , punching

Ultrastructural studies of the guinea pig tympanic membrane failed to reveal specific morphological features that could be associated with migration. A staining method was used to study epithelial migration on 68 normal guinea pig tympanic membranes. A very predictable migratory pattern emerged which was neither influenced by perforation or ventilating tube insertion. Clinical studies in children on 61 normal tympanic membranes revealed a rapid migration which was unchanged by middle ear effusion. A centrifugal pattern of migration was observed in relation to the 23 chronic perforations studied. The kinetics of epithelium in relation to 41 ventilating tubes and in 23 retraction pockets is described.

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