Asthma and Atopic Eczema

Discussion The clinical diagnosis was multiple myeloma of the IgG lambda type with soft tissue metastasis to the forehead from an underlying lytic bone lesion of the skull. The forehead cystic mass was not aspirated or biopsied for fear of introducing infection to the epidura and meninges in a compromised host (see Figures I and 2). In spite of three cyclical courses of busulphan (Myleran) and prednisone followed by melphalan and prednisone therapy and several units of washed packed cell transfusions, chemotherapy did not affect or reduce the size of the cystic mass in the forehead nor alter the course of the disease. She died one and a half years later from renal failure and intercurrent infection. In retrospect, local irradiation to the forehead lesion may have been beneficial in reducing the size of the tumour.