Value of Xenografts in the Investigation of Prostatic Function: Preliminary Communication | Zendy

Mark Jones | Zendy; Grant Williams | Zendy; Andrew Davies | Zendy

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Value of Xenografts in the Investigation of Prostatic Function: Preliminary Communication

Author(s) -

Mark Jones,

Grant Williams,

Andrew Davies

Publication year - 1980

Publication title -

journal of the royal society of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.38

H-Index - 81

eISSN - 1758-1095

pISSN - 0141-0768

DOI - 10.1177/014107688007301005

Subject(s) - value (mathematics) , medicine , function (biology) , testosterone (patch) , cancer research , oncology , pathology , biology , computer science , evolutionary biology , machine learning

Two of 33 prostatic tumour xenografts were established and passaged. Testosterone supplementation did not improve tumour take rates. The histological grade of the parent tumour was the principal factor affecting xenograft survival. Preliminary studies on established tumour xenografts suggest that their value lies in the study of tumour biology, and that they have no direct therapeutic application at present.

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