Open AccessHow Reliable Are Sino-Nasal Cell Lines for Studying the Pathophysiology of Chronic Rhinosinusitis?
Author(s) -
Stephen Ball,
Monika Suwara,
Lee A. Borthwick,
J. A. Wilson,
Derek A. Mann,
Andrew J. Fisher
Publication year - 2014
Publication title -
annals of otology rhinology and laryngology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.65
H-Index - 91
eISSN - 1943-572X
pISSN - 0003-4894
DOI - 10.1177/0003489414565003
Subject(s) - cell culture , pathophysiology , nasal polyps , chronic rhinosinusitis , phenotype , cell , disease , immunology , cell type , mesenchymal stem cell , biology , medicine , pathology , gene , genetics
Well-characterized cell lines represent useful scientific tools to study the pathophysiology of human disease. Chronic rhinosinusitis (CRS) is a very common condition, though the number of CRS cell lines is limited, as are data showing how closely they resemble primary cells.
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