Photothermal Optical Coherence Tomography of Anti-Angiogenic Treatment in the Mouse Retina Using Gold Nanorods as Contrast Agents | Zendy

Andrew Y. Gordon | Zendy; Maryse Lapierre-Landry | Zendy; Melissa C. Skala | Zendy; John S. Penn | Zendy

Open Access

Photothermal Optical Coherence Tomography of Anti-Angiogenic Treatment in the Mouse Retina Using Gold Nanorods as Contrast Agents

Author(s) -

Andrew Y. Gordon,

Maryse Lapierre-Landry,

Melissa C. Skala,

John S. Penn

Publication year - 2019

Publication title -

translational vision science and technology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.508

H-Index - 21

ISSN - 2164-2591

DOI - 10.1167/tvst.8.3.18

Subject(s) - photothermal therapy , optical coherence tomography , in vivo , retina , preclinical imaging , molecular imaging , pathology , choroidal neovascularization , medicine , lesion , nanorod , biomedical engineering , neovascularization , ophthalmology , materials science , cancer research , angiogenesis , macular degeneration , biology , nanotechnology , neuroscience , microbiology and biotechnology

This study shows that PTOCT imaging of GNR in the LCNV model can be used to detect clinically relevant, anti-VEGF-induced changes that are not visible using standard OCT systems. In the future this technology could be used to aid in early detection of disease, monitoring disease progress, and assessing its response to therapies.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research