Liquid Biopsy of Vitreous Reveals an Abundant Vesicle Population Consistent With the Size and Morphology of Exosomes | Zendy

Yuanjun Zhao | Zendy; Sarah R. Weber | Zendy; Joshua Lease | Zendy; Mariano Russo | Zendy; Christopher A. Siedlecki | Zendy; LiChong Xu | Zendy; Han Chen | Zendy; Weiwei Wang | Zendy; Michael Ford | Zendy; Rafael Simó | Zendy; Jeffrey M. Sundstrom | Zendy

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Liquid Biopsy of Vitreous Reveals an Abundant Vesicle Population Consistent With the Size and Morphology of Exosomes

Author(s) -

Yuanjun Zhao,

Sarah R. Weber,

Joshua Lease,

Mariano Russo,

Christopher A. Siedlecki,

LiChong Xu,

Han Chen,

Weiwei Wang,

Michael Ford,

Rafael Simó,

Jeffrey M. Sundstrom

Publication year - 2018

Publication title -

translational vision science and technology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.508

H-Index - 21

ISSN - 2164-2591

DOI - 10.1167/tvst.7.3.6

Subject(s) - vitrectomy , microvesicles , vesicle , exosome , epiretinal membrane , population , retinal detachment , retina , retinal , nanoparticle tracking analysis , chemistry , pars plana , microbiology and biotechnology , pathology , biology , medicine , ophthalmology , biochemistry , visual acuity , microrna , gene , neuroscience , membrane , environmental health

The identification of vitreous exosomes lays the groundwork for a transformed understanding of pathophysiology and treatment mechanisms in retinal disease, and further validates the use of vitreous as a proximal biofluid of the retina.

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