Development of an Experimental Drug Eluting Suprachoroidal Microstent as Glaucoma Drainage Device | Zendy

Marina Hovakimyan | Zendy; Stefan Siewert | Zendy; W. J. Schmidt | Zendy; Katrin Sternberg | Zendy; Thomas Reske | Zendy; Oliver Stachs | Zendy; Rudolf Guthoff | Zendy; Andreas Wree | Zendy; Martin Witt | Zendy; KlausPeter Schmitz | Zendy; Reto Allemann | Zendy

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Development of an Experimental Drug Eluting Suprachoroidal Microstent as Glaucoma Drainage Device

Author(s) -

Marina Hovakimyan,

Stefan Siewert,

W. J. Schmidt,

Katrin Sternberg,

Thomas Reske,

Oliver Stachs,

Rudolf Guthoff,

Andreas Wree,

Martin Witt,

KlausPeter Schmitz,

Reto Allemann

Publication year - 2015

Publication title -

translational vision science and technology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.508

H-Index - 21

ISSN - 2164-2591

DOI - 10.1167/tvst.4.3.14

Subject(s) - glaucoma , medicine , ophthalmology , latanoprost , optometry

The presented data serve as a proof of principle study for the concept of a suprachoroidal drug eluting microstent. Future device improvements will be focused on the design of LDD systems and the use of specific anti-inflammatory or antifibrotic agents with less cytotoxicity compared to MitC or PTX. Long-term animal studies using a reliable glaucoma model will be a further step towards clinical application and improvement of surgical glaucoma therapy.

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