Reduced Dendritic Spines in the Visual Cortex Contralateral to the Optic Nerve Crush Eye in Adult Mice
Author(s) -
Zongyi Zhan,
Yali Wu,
Zitian Liu,
Yadan Quan,
Deling Li,
Yiru Huang,
Shana Yang,
Kaili Wu,
Lianyan Huang,
Minbin Yu
Publication year - 2020
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.61.10.55
Subject(s) - glial fibrillary acidic protein , dendritic spine , tropomyosin receptor kinase b , retinal , retina , nerve fiber layer , microglia , neun , astrocyte , chemistry , biology , optic nerve , pathology , anatomy , neuroscience , medicine , ophthalmology , immunohistochemistry , neurotrophic factors , receptor , central nervous system , immunology , hippocampal formation , inflammation
Dendritic spines were reduced in the V1 region contralateral to the ONC eye in adult mice. Reactive astrocytes and decreased TrkB may be associated with the reduced dendritic spines.
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