Association of Glaucoma Risk Genes with Retinal Nerve Fiber Layer in a Multi-ethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study | Zendy

Xiaoran Chai | Zendy; Kok Yao Low | Zendy; YihChung Tham | Zendy; Miao Li Chee | Zendy; Sahil Thakur | Zendy; Liang Zhang | Zendy; Nicholas Y.Q. Tan | Zendy; Chiea Chuen Khor | Zendy; Tin Aung | Zendy; Tien Yin Wong | Zendy; ChingYu Cheng | Zendy

Open Access

Association of Glaucoma Risk Genes with Retinal Nerve Fiber Layer in a Multi-ethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study

Author(s) -

Xiaoran Chai,

Kok Yao Low,

YihChung Tham,

Miao Li Chee,

Sahil Thakur,

Liang Zhang,

Nicholas Y.Q. Tan,

Chiea Chuen Khor,

Tin Aung,

Tien Yin Wong,

ChingYu Cheng

Publication year - 2020

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.61.10.37

Subject(s) - nerve fiber layer , glaucoma , epidemiology , retinal , ethnic group , medicine , optometry , association (psychology) , ophthalmology , political science , psychology , law , psychotherapist

Of the 35 glaucoma identified risk loci, only SIX6 is significantly and independently associated with thinner RNFL. Our study further supports the involvement of SIX6 with RNFL thickness and pathogensis of glaucoma.

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