Topical Pergolide Enhance Corneal Nerve Regrowth Following Induced Corneal Abrasion | Zendy

Xiaohui Zhang | Zendy; Santosh Kumar Muddana | Zendy; Sangeetha Ravi Kumar | Zendy; Joshua N. Burton | Zendy; Pratima Labroo | Zendy; Jill Shea | Zendy; Parker Stocking | Zendy; Cornelia Siegl | Zendy; Bonnie Archer | Zendy; Jayant Agarwal | Zendy; Balamurali K. Ambati | Zendy

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Topical Pergolide Enhance Corneal Nerve Regrowth Following Induced Corneal Abrasion

Author(s) -

Xiaohui Zhang,

Santosh Kumar Muddana,

Sangeetha Ravi Kumar,

Joshua N. Burton,

Pratima Labroo,

Jill Shea,

Parker Stocking,

Cornelia Siegl,

Bonnie Archer,

Jayant Agarwal,

Balamurali K. Ambati

Publication year - 2020

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.61.1.4

Subject(s) - pergolide , cornea , nerve growth factor , axon , medicine , agonist , ophthalmology , endocrinology , anesthesia , anatomy , dopamine agonist , receptor

We demonstrated that pergolide can act to promote an increase in NGF which promotes corneal nerve regeneration and would therefore improve corneal sensation and visual acuity in eyes with peripheral neurotrophic keratopathy.

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