Open AccessHIF1α-mediated TRAIL Expression Regulates Lacrimal Gland Inflammation in Dry Eye Disease
Author(s) -
Yong Woo Ji,
JoonHyung Lee,
Eun Young Choi,
Hyun Goo Kang,
Kyoung Yul Seo,
Jong Suk Song,
Hyeon Chang Kim,
Hyung Keun Lee
Publication year - 2020
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.61.1.3
Subject(s) - lacrimal gland , inflammation , medicine , microbiology and biotechnology , biology , ophthalmology , endocrinology , pathology
Our findings offer novel insight into the regulatory function of acinar cell-derived TRAIL in limiting inflammatory damage and could be implicated in the development of potential therapeutic strategies for DED.
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