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Chemokine Receptor Expression Pattern Correlates to Progression of Conjunctival Melanocytic Lesions
Author(s) -
Jolique A. van Ipenburg,
Nadine E. de Waard,
Nicole C. Naus,
Martine J. Jager,
Dion Paridaens,
Robert M. Verdijk
Publication year - 2019
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.19-27162
Subject(s) - melanoma , chemokine receptor , metastasis , medicine , atypia , c c chemokine receptor type 7 , pathology , immunohistochemistry , chemokine , cancer research , receptor , cancer
Chemokines play a role in the progression and metastatic spread of both cutaneous and uveal melanomas. The aim of this study was to examine the prognostic value of expression of chemokine receptors CCR7, CXCR4, and CCR10 in conjunctival melanocytic lesions.

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