Dysregulated Tear Fluid Nociception-Associated Factors, Corneal Dendritic Cell Density, and Vitamin D Levels in Evaporative Dry Eye | Zendy

Pooja Khamar | Zendy; Archana Padmanabhan Nair | Zendy; Rohit Shetty | Zendy; Tanuja Vaidya | Zendy; Murali Subramani | Zendy; Ponnalagu Murugeswari | Zendy; Kamesh Dhamodaran | Zendy; Sharon D’Souza | Zendy; Anuprita Ghosh | Zendy; Natasha Pahuja | Zendy; Rashmi Deshmukh | Zendy; Prerna Ahuja | Zendy; Kanchan Sainani | Zendy; Rudy M.M.A. Nuijts | Zendy; Debashish Das | Zendy; Arkasubhra Ghosh | Zendy; Swaminathan Sethu | Zendy

Open Access

Dysregulated Tear Fluid Nociception-Associated Factors, Corneal Dendritic Cell Density, and Vitamin D Levels in Evaporative Dry Eye

Author(s) -

Pooja Khamar,

Archana Padmanabhan Nair,

Rohit Shetty,

Tanuja Vaidya,

Murali Subramani,

Ponnalagu Murugeswari,

Kamesh Dhamodaran,

Sharon D’Souza,

Anuprita Ghosh,

Natasha Pahuja,

Rashmi Deshmukh,

Prerna Ahuja,

Kanchan Sainani,

Rudy M.M.A. Nuijts,

Debashish Das,

Arkasubhra Ghosh,

Swaminathan Sethu

Publication year - 2019

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.19-26914

Subject(s) - medicine , ophthalmology , tears , cornea , nerve plexus , multiplex , pathology , surgery , bioinformatics , biology

Altered tear fluid soluble factors with potential to modulate nociception exhibited a distinct association with ocular surface discomfort status, TBUT, STI, and cDCD. This implies a functional relationship between the various tear-soluble factors and dry eye pathogenesis, indicating new molecular targets for designing targeted therapies.

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