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Overt Proteinuria, Moderately Reduced eGFR and Their Combination Are Predictive of Severe Diabetic Retinopathy or Diabetic Macular Edema in Diabetes
Author(s) -
Masahiko Yamamoto,
Kazuya Fujihara,
Masahiro Ishizawa,
TAEKO OSAWA,
Masanori Kaneko,
Hajime Ishiguro,
Yasuhiro Matsubayashi,
Hiroyasu Seida,
NAUTA YAMANAKA,
Shiro Tanaka,
Satoru Kodama,
H. Hasebe,
Hirohito Sone
Publication year - 2019
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.19-26749
Subject(s) - medicine , proteinuria , diabetic retinopathy , diabetes mellitus , hazard ratio , confidence interval , renal function , incidence (geometry) , proportional hazards model , urology , albuminuria , gastroenterology , endocrinology , kidney , physics , optics
Since the combined effects of proteinuria and a moderately decreased eGFR on incident severe eye complications in patients with diabetes are still largely unknown, these associations were determined in a large historical cohort of Japanese patients with diabetes mellitus.

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