Tau Is Involved in Death of Retinal Ganglion Cells of Rats From Optic Nerve Crush
Author(s) -
Hidehiro Oku,
Teruyo Kida,
Taeko Horie,
Koichiro Taki,
Masashi Mimura,
Shota Kojima,
Tsunehiko Ikeda
Publication year - 2019
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.19-26683
Subject(s) - neuroprotection , retina , optic nerve , gene silencing , retinal , retinal ganglion cell , small interfering rna , microbiology and biotechnology , autophagy , immunohistochemistry , chemistry , tau protein , ophthalmology , biology , medicine , endocrinology , neuroscience , gene , rna , biochemistry , apoptosis , disease , alzheimer's disease
To determine whether tauopathies are associated with impaired autophagy and involved in the death of retinal ganglion cells (RGCs) of rats from an optic nerve crush (ONC).
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