Open AccessActivation of the BMP4/Smad1 Pathway Promotes Retinal Ganglion Cell Survival and Axon Regeneration
Author(s) -
Adam Thompson,
Martin Berry,
Ann Logan,
Zubair Ahmed
Publication year - 2019
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.18-26449
Subject(s) - regeneration (biology) , retinal ganglion cell , axon , ganglion , retina , neuroscience , retinal , retinal regeneration , medicine , microbiology and biotechnology , biology , ophthalmology
We investigate if the BMP4/Smad1 intracellular signaling pathway is neuroprotective and axogenic in adult rodent retinal ganglion cells (RGC) in vivo and in vitro.
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