Resveratrol Inhibits Wound Healing and Lens Fibrosis: A Putative Candidate for Posterior Capsule Opacification Prevention | Zendy

Andrew J. O. Smith | Zendy; Julie A. Eldred | Zendy; I. Michael Wormstone | Zendy

Open Access

Resveratrol Inhibits Wound Healing and Lens Fibrosis: A Putative Candidate for Posterior Capsule Opacification Prevention

Author(s) -

Andrew J. O. Smith,

Julie A. Eldred,

I. Michael Wormstone

Publication year - 2019

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.18-26248

Subject(s) - myofibroblast , wound healing , resveratrol , western blot , fibrosis , extracellular matrix , andrology , fetal bovine serum , microbiology and biotechnology , cell , pathology , biology , medicine , immunology , pharmacology , biochemistry , gene

Posterior capsule opacification (PCO) is a common complication of cataract surgery. In addition to improved surgical methods and IOL designs, it is likely additional agents will be needed to improve patient outcomes. Presently no pharmacological agent is in clinical use to prevent PCO. Here we investigate the putative ability of resveratrol (RESV), a naturally occurring polyphenol, as a therapeutic agent.

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