Multiple Differentially Methylated Regions Specific to Keratoconus Explain Known Keratoconus Linkage Loci | Zendy

Michał Kabza | Zendy; Justyna A. Karolak | Zendy; Małgorzata Rydzanicz | Zendy; Monika Udziela | Zendy; Piotr Gasperowicz | Zendy; Rafał Płoski | Zendy; Jacek P. Szaflik | Zendy; Marzena Gajęcka | Zendy

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Multiple Differentially Methylated Regions Specific to Keratoconus Explain Known Keratoconus Linkage Loci

Author(s) -

Michał Kabza,

Justyna A. Karolak,

Małgorzata Rydzanicz,

Monika Udziela,

Piotr Gasperowicz,

Rafał Płoski,

Jacek P. Szaflik,

Marzena Gajęcka

Publication year - 2019

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.18-25916

Subject(s) - biology , dna methylation , differentially methylated regions , wnt signaling pathway , genetics , epigenetics , transcriptome , methylation , gene , keratoconus , epigenomics , bisulfite sequencing , gene expression , cornea , neuroscience

Keratoconus (KTCN) is a complex eye disorder resulting in loss of visual function. Its development is affected by genetic and environmental components. The aim of this study was to unravel the role of epigenetic factors in KTCN.

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