Following the Status of Visual Cortex Over Time in Patients With Macular Degeneration Reveals Atrophy of Visually Deprived Brain Regions
Author(s) -
Rachel L. W. Hanson,
Richard Gale,
André Gouws,
Archana Airody,
Martin T.W. Scott,
Farah Akthar,
Sophie Waterson,
Mason Wells,
Aaron J. Wright,
Kerry Bell,
Edward H. Silson,
Heidi A. Baseler,
Antony B. Morland
Publication year - 2019
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.18-25823
Subject(s) - atrophy , lesion , visual cortex , occipital lobe , macular degeneration , medicine , cortex (anatomy) , retina , retinal , visual acuity , temporal lobe , ophthalmology , neuroscience , pathology , psychology , radiology , epilepsy
Previous research has shown atrophy of visual cortex can occur in retinotopic representations of retinal lesions resulting from eye disease. However, the time course of atrophy cannot be established from these cross-sectional studies, which included patients with longstanding disease of varying severity. Our aim, therefore, was to measure visual cortical structure over time in participants after onset of unilateral visual loss resulting from AMD.
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