Open AccessOptic Nerve Lipidomics Reveal Impaired Glucosylsphingosine Lipids Pathway in Glaucoma
Author(s) -
Muhammad Z. Chauhan,
Ann-Katrin Valencia,
Maria Carmen Piqueras,
Mabel EnriquezAlgeciras,
Sanjoy K. Bhattacharya
Publication year - 2019
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.18-25802
Subject(s) - western blot , lipidomics , sphingolipid , ceramide , glaucoma , chemistry , optic nerve , chromatography , microbiology and biotechnology , biochemistry , ophthalmology , biology , medicine , apoptosis , gene
To determine major differences in lipid profile between human control and glaucomatous optic nerve. To assess major enzymes in lipid pathway if aberration is revealed for a lipid class by profiling.
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