MicroRNA-Related Genetic Variants Are Associated With Diabetic Retinopathy in Type 1 Diabetes Mellitus
Author(s) -
Ebony Liu,
Georgia Kaidonis,
Bennet J. McComish,
Mark Gillies,
Sotoodeh Abhary,
Rohan W. Essex,
John H. Chang,
Bishwanath Pal,
Mark Daniell,
Stewart Lake,
Nikolai Petrovsky,
Alex W. Hewitt,
Alicia J. Jenkins,
Ecosse L. Lamoureux,
Jonathan Gleadle,
Jamie E. Craig,
Kathryn P. Burdon
Publication year - 2019
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.18-25570
Subject(s) - diabetic retinopathy , microrna , medicine , type 2 diabetes mellitus , diabetes mellitus , type 2 diabetes , bioinformatics , ophthalmology , genetics , biology , endocrinology , gene
Few studies have explored the association of genetic variants in microRNA genes and binding sites with diabetic retinopathy (DR) in type 1 diabetes. We conducted a genome-wide scan for single nucleotide polymorphisms (SNPs) in these genes by using data from a genome-wide association study (GWAS).
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