Open AccessDual Properties of Lactate in Müller Cells: The Effect of GPR81 Activation
Author(s) -
Rupali Vohra,
Blanca I. Aldana,
Helle S. Waagepetersen,
Linda H. Bergersen,
Miriam Kolko
Publication year - 2019
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.18-25458
Subject(s) - receptor , medicine , lactate dehydrogenase , biology , endocrinology , biochemistry , chemistry , enzyme
Besides being actively metabolized, lactate may also function as a signaling molecule by activation of the G-protein-coupled receptor 81 (GPR81). Thus, we aimed to characterize the metabolic effects of GPR81 activation in Müller cells.
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