Retinal and Cerebral Microvasculopathy: Relationships and Their Genetic Contributions
Author(s) -
Jacoba A. van de Kreeke,
HoangTon Nguyen,
Elles Konijnenberg,
Jori Tomassen,
Anouk den Braber,
Mara ten Kate,
Carole H. Sudre,
Frederik Barkhof,
Dorret I. Boomsma,
H. Stevie Tan,
Frank D. Verbraak,
Pieter Jelle Visser
Publication year - 2018
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.18-25341
Subject(s) - hyperintensity , retinal , white matter , monozygotic twin , cardiology , tortuosity , twin study , medicine , ophthalmology , anatomy , magnetic resonance imaging , biology , radiology , chemistry , genetics , organic chemistry , porosity , heritability
Retinal microvasculopathy may reflect small vessel disease in the brain. Here we test the relationships between retinal vascular parameters and small vessel disease, the influence of cardiovascular risk factors on these relationships, and their common genetic background in a monozygotic twin cohort.
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