Vascular Interstitial Cells in Retinal Arteriolar Annuli Are Altered During Hypertension | Zendy

David Ramos | Zendy; Joana Catita | Zendy; Mariana LópezLuppo | Zendy; Andreia Valença | Zendy; Aina Bonet | Zendy; Ana Carretero | Zendy; Marc Navarro | Zendy; Víctor Nacher | Zendy; Simón MéndezFerrer | Zendy; Anna Meseguer | Zendy; Alba Casellas | Zendy; Luísa Mendes-Jorge | Zendy; Jesús Ruberte | Zendy

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Vascular Interstitial Cells in Retinal Arteriolar Annuli Are Altered During Hypertension

Author(s) -

David Ramos,

Joana Catita,

Mariana LópezLuppo,

Andreia Valença,

Aina Bonet,

Ana Carretero,

Marc Navarro,

Víctor Nacher,

Simón MéndezFerrer,

Anna Meseguer,

Alba Casellas,

Luísa Mendes-Jorge,

Jesús Ruberte

Publication year - 2019

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.18-25000

Subject(s) - pericyte , interstitial cell of cajal , microbiology and biotechnology , retina , biology , nestin , retinal , interstitial cell , pathology , population , endothelial stem cell , endocrinology , immunohistochemistry , stem cell , immunology , medicine , biochemistry , environmental health , neural stem cell , neuroscience , in vitro

It has been suggested that arteriolar annuli localized in retinal arterioles regulate retinal blood flow acting as sphincters. Here, the morphology and protein expression profile of arteriolar annuli have been analyzed under physiologic conditions in the retina of wild-type, β-actin-Egfp, and Nestin-gfp transgenic mice. Additionally, to study the effect of hypertension, the KAP transgenic mouse has been used.

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