Induction of Apoptosis in Pterygium Cells by Antagonists of Growth Hormone–Releasing Hormone Receptors
Author(s) -
Yongjie Qin,
Wai Kit Chu,
Li Huang,
Clara Hoi Yen Ng,
Tommy C.Y. Chan,
Di Cao,
Cheng Yang,
Liang Zhang,
Shao Ping Huang,
Juan Li,
Hong-Liang Lin,
Wen Qian Li,
Li Chen,
Andrew V. Schally,
Sun On Chan,
Hong Yang Zhang,
Chi Pui Pang
Publication year - 2018
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.18-24751
Subject(s) - downregulation and upregulation , apoptosis , growth hormone–releasing hormone , immunofluorescence , receptor , hormone receptor , biology , endocrinology , flow cytometry , medicine , hormone , microbiology and biotechnology , immunology , growth hormone , antibody , cancer , biochemistry , breast cancer , gene
The aim of the study was to investigate the signaling of growth hormone-releasing hormone receptor (GHRH-R) in the pathogenesis of pterygium and determine the apoptotic effect of GHRH-R antagonist on pterygium epithelial cells (PECs).
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom