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Induction of Apoptosis in Pterygium Cells by Antagonists of Growth Hormone–Releasing Hormone Receptors
Author(s) -
Yongjie Qin,
Wai Kit Chu,
Li Huang,
Clara Hoi Yen Ng,
Tommy C.Y. Chan,
Di Cao,
Cheng Yang,
Liang Zhang,
Shao Ping Huang,
Juan Li,
Hong-Liang Lin,
Wen Qian Li,
Li Chen,
Andrew V. Schally,
Sun On Chan,
Hong Yang Zhang,
Chi Pui Pang
Publication year - 2018
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.18-24751
Subject(s) - downregulation and upregulation , apoptosis , growth hormone–releasing hormone , immunofluorescence , receptor , hormone receptor , biology , endocrinology , flow cytometry , medicine , hormone , microbiology and biotechnology , immunology , growth hormone , antibody , cancer , biochemistry , breast cancer , gene
The aim of the study was to investigate the signaling of growth hormone-releasing hormone receptor (GHRH-R) in the pathogenesis of pterygium and determine the apoptotic effect of GHRH-R antagonist on pterygium epithelial cells (PECs).

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