Open AccessDecreasedd -Serine Levels Prevent Retinal Ganglion Cell Apoptosis in a Glaucomatous Animal Model
Author(s) -
Xuejin Zhang,
Rong Zhang,
Xujiao Zhou,
Jihong Wu
Publication year - 2018
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.18-24691
Subject(s) - tunel assay , retina , serine , retinal ganglion cell , ganglion cell layer , apoptosis , glaucoma , retinal , ophthalmology , chemistry , biology , medicine , biochemistry , neuroscience , enzyme
The purpose of this study was to determine d-Serine and d-Serine synthetase serine racemase (SR) expression and whether decreased d-Serine expression has protective effects on retinal ganglion cells (RGCs) in a glaucomatous animal model.
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