Disabled-2 (DAB2) Overexpression Inhibits Monocyte-Derived Dendritic Cells' Function in Vogt-Koyanagi-Harada Disease
Author(s) -
Shenglan Yi,
Rui Chang,
Jianping Hu,
Yiguo Qiu,
Qingfeng Wang,
Qingfeng Cao,
Gangxiang Yuan,
Guannan Su,
Chunjiang Zhou,
Yao Wang,
Aize Kijlstra,
Peizeng Yang
Publication year - 2018
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.18-24630
Subject(s) - cd86 , flow cytometry , biology , dendritic cell , immune system , autophagy , immunology , cancer research , microbiology and biotechnology , t cell , apoptosis , biochemistry
Recent studies reported that the tumor suppressor disabled-2 (DAB2) is a negative regulator of immune function. In this study, we investigated the role of DAB2 in monocyte-derived dendritic cells (DCs) from Vogt-Koyanagi-Harada disease (VKH) patients.
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