Neuroprotective Effects of FGF2 and Minocycline in Two Animal Models of Inherited Retinal Degeneration | Zendy

Johnny Di Pierdomenico | Zendy; Rebecca Scholz | Zendy; Francisco J. ValienteSoriano | Zendy; M.C. Sánchez-Migallón | Zendy; Manuel VidalSanz | Zendy; Thomas Langmann | Zendy; Marta AgudoBarriuso | Zendy; Diego GarcíaAyuso | Zendy; María Paz VillegasPérez | Zendy

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Neuroprotective Effects of FGF2 and Minocycline in Two Animal Models of Inherited Retinal Degeneration

Author(s) -

Johnny Di Pierdomenico,

Rebecca Scholz,

Francisco J. ValienteSoriano,

M.C. Sánchez-Migallón,

Manuel VidalSanz,

Thomas Langmann,

Marta AgudoBarriuso,

Diego GarcíaAyuso,

María Paz VillegasPérez

Publication year - 2018

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.18-24621

Subject(s) - minocycline , pedf , ciliary neurotrophic factor , outer nuclear layer , retinal degeneration , neuroprotection , microglia , neurotrophic factors , retinal , neurotrophin , retina , intraperitoneal injection , retinitis pigmentosa , biology , neuroscience , pathology , endocrinology , medicine , ophthalmology , immunology , inflammation , biochemistry , receptor , antibiotics

The purpose of this study was to study the effect of minocycline and several neurotrophic factors, alone or in combination, on photoreceptor survival and macro/microglial reactivity in two rat models of retinal degeneration.

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