Photoreceptor Progenitors Depend Upon Coordination ofgdf6a,thrβ, andtbx2bto Generate Precise Populations of Cone Photoreceptor Subtypes | Zendy

Michèle G. DuVal | Zendy; W. Ted Allison | Zendy

Open Access

Photoreceptor Progenitors Depend Upon Coordination ofgdf6a,thrβ, andtbx2bto Generate Precise Populations of Cone Photoreceptor Subtypes

Author(s) -

Michèle G. DuVal,

W. Ted Allison

Publication year - 2018

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.18-24461

Subject(s) - zebrafish , mutant , biology , phenotype , gene knockdown , retina , microbiology and biotechnology , retinal , genetics , gene , biochemistry , neuroscience

Replacing cone photoreceptors, the units of the retina necessary for daytime vision, depends upon the successful production of a full variety of new cones from, for example, stem cells. Using genetic experiments in a model organism with high cone diversity, zebrafish, we map the intersecting effects of cone development factors gdf6a, tbx2b, and thrβ.

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