Expression Profiling Analysis Reveals Key MicroRNA–mRNA Interactions in Early Retinal Degeneration in Retinitis Pigmentosa | Zendy

Ander Anasagasti | Zendy; Maitane Ezquerra-Inchausti | Zendy; Olatz Barandika | Zendy; Maider MuñozCulla | Zendy; María M. Caffarel | Zendy; David Otaegui | Zendy; Adolfo López de Munaín | Zendy; Javier RuizEderra | Zendy

Open Access

Expression Profiling Analysis Reveals Key MicroRNA–mRNA Interactions in Early Retinal Degeneration in Retinitis Pigmentosa

Author(s) -

Ander Anasagasti,

Maitane Ezquerra-Inchausti,

Olatz Barandika,

Maider MuñozCulla,

María M. Caffarel,

David Otaegui,

Adolfo López de Munaín,

Javier RuizEderra

Publication year - 2018

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.18-24091

Subject(s) - retinitis pigmentosa , retinal degeneration , microrna , retinal , biology , retina , gene therapy of the human retina , messenger rna , macular degeneration , genetics , pathology , gene , neuroscience , ophthalmology , medicine , biochemistry

The aim of this study was to identify differentially expressed microRNAs (miRNAs) that might play an important role in the etiology of retinal degeneration in a genetic mouse model of retinitis pigmentosa (rd10 mice) at initial stages of the disease.

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