Interaction Between CCR6+ Th17 Cells and CD34+ Fibrocytes Promotes Inflammation: Implications in Graves' Orbitopathy in Chinese Population | Zendy

Sijie Fang | Zendy; Yazhuo Huang | Zendy; Xingtong Liu | Zendy; Sisi Zhong | Zendy; Ningjian Wang | Zendy; Binbin Zhao | Zendy; Yinwei Li | Zendy; Jing Sun | Zendy; Yang Wang | Zendy; Shuo Zhang | Zendy; Ping Gu | Zendy; Huifang Zhou | Zendy; Bin Li | Zendy; Xianqun Fan | Zendy

Open Access

Interaction Between CCR6⁺ Th17 Cells and CD34⁺ Fibrocytes Promotes Inflammation: Implications in Graves' Orbitopathy in Chinese Population

Author(s) -

Sijie Fang,

Yazhuo Huang,

Xingtong Liu,

Sisi Zhong,

Ningjian Wang,

Binbin Zhao,

Yinwei Li,

Jing Sun,

Yang Wang,

Shuo Zhang,

Ping Gu,

Huifang Zhou,

Bin Li,

Xianqun Fan

Publication year - 2018

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.18-24008

Subject(s) - fibrocyte , immunology , population , cd86 , c c chemokine receptor type 6 , rar related orphan receptor gamma , medicine , cytokine , cd80 , flow cytometry , inflammation , chemokine , chemistry , t cell , cd40 , immune system , pathology , cytotoxic t cell , chemokine receptor , foxp3 , in vitro , biochemistry , environmental health

Recent reports suggest that Th17 immunity and bone marrow-derived CD34+ fibrocytes contribute to the pathogenesis of Graves' orbitopathy (GO). This study investigated interactions between Th17 cells and fibrocytes in GO inflammation in Chinese subjects.

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