Pharmacokinetics of Caffeine in the Lens Capsule/Epithelium After Peroral Intake: A Pilot Randomized Controlled Study
Author(s) -
Martin Kronschläger,
Thomas Stimpfl,
Manuel Ruiß,
Nino Hirnschall,
Christoph Leisser,
Oliver Findl
Publication year - 2018
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.18-23963
Subject(s) - pharmacokinetics , caffeine , capsule , medicine , pilot trial , lens capsule , randomized controlled trial , ophthalmology , pharmacology , biology , botany , glaucoma
To determine the pharmacokinetics of perorally administered caffeine, a widely consumed and potent dietary antioxidant, in the anterior lens capsule and lens epithelial cells, a crucial cell monolayer for cataract development.
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