Open AccessPEDF Reduces the Severity of Herpetic Simplex Keratitis in Mice
Author(s) -
Xiao Ying Tian,
Tongsong Wang,
Songmei Zhang,
Qian Wang,
Xiaoli Hu,
Ge Cheng,
Lixin Xie,
Qingjun Zhou
Publication year - 2018
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.18-23942
Subject(s) - pedf , keratitis , corneal neovascularization , herpes simplex virus , neovascularization , medicine , cornea , proinflammatory cytokine , immunology , inflammation , pathology , biology , cancer research , ophthalmology , angiogenesis , virus
The purpose of this study was to explore the effects of pigment epithelium derived factor (PEDF) and PEDF-derived peptides Mer44 and Mer34 on the severity of herpetic simplex keratitis (HSK) in mice.
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