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Comparing Clinical Perimetry and Population Receptive Field Measures in Patients with Choroideremia
Author(s) -
Edward H. Silson,
Tomas S. Alemán,
Aimee Willett,
Leona Serrano,
Denise J. Pearson,
Andreas M. Rauschecker,
Albert M. Maguire,
Chris I. Baker,
Jean Bennett,
Manzar Ashtari
Publication year - 2018
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.18-23929
Subject(s) - choroideremia , medicine , ophthalmology , optometry , receptive field , psychology , neuroscience , retinal
Choroideremia (CHM) is an X-linked recessive form of hereditary retinal degeneration, which, at advanced stages, leaves only small central islands of preserved retinal tissue. Unlike many other retinal diseases, the spared tissue in CHM supports excellent central vision and stable fixation. Such spared topography in CHM presents an ideal platform to explore the relationship between preserved central retinal structure and the retinotopic organization of visual cortex by using functional magnetic resonance imaging (fMRI).

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