Visualizing the Fate of Transplanted K14-Confetti Corneal Epithelia in a Mouse Model of Limbal Stem Cell Deficiency | Zendy

Alexander Richardson | Zendy; Mijeong Park | Zendy; Stephanie L. Watson | Zendy; Denis Wakefield | Zendy; Nick Di Girolamo | Zendy

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Visualizing the Fate of Transplanted K14-Confetti Corneal Epithelia in a Mouse Model of Limbal Stem Cell Deficiency

Author(s) -

Alexander Richardson,

Mijeong Park,

Stephanie L. Watson,

Denis Wakefield,

Nick Di Girolamo

Publication year - 2018

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.17-23557

Subject(s) - stem cell , biology , limbal stem cell , transplantation , corneal epithelium , cornea , phenotype , transdifferentiation , microbiology and biotechnology , pathology , medicine , biochemistry , neuroscience , gene

Therapies for limbal stem cell deficiency (LSCD) include stem cell (SC) grafts that regenerate the damaged ocular surface. However, the fate of transplanted cells is ill-defined. We addressed this limitation using primary corneal epithelial cells from K14-Confetti mice.

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