Potential Role of Zinc Dyshomeostasis in Matrix Metalloproteinase-2 and -9 Activation and Photoreceptor Cell Death in Experimental Retinal Detachment
Author(s) -
Jeong A Choi,
Yoon Jeon Kim,
Bora Seo,
JaeYoung Koh,
Young Hee Yoon
Publication year - 2018
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.17-23502
Subject(s) - programmed cell death , photoreceptor cell , matrix metalloproteinase , retina , retinal , chemistry , extracellular matrix , microbiology and biotechnology , biology , apoptosis , biochemistry , neuroscience
We investigated whether zinc dyshomeostasis, a known mechanism of cell death in acute brain injury, contributes to the activation of matrix metalloproteinases (MMPs) and photoreceptor cell death in experimental retinal detachment (RD).
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