Association of Long Noncoding RNAs Polymorphisms With Ankylosing Spondylitis, Vogt-Koyanagi-Harada Disease, and Behcet's Disease | Zendy

Yingying Yue | Zendy; Jun Zhang | Zendy; Yang Lu | Zendy; Shengyun Liu | Zendy; Jian Qi | Zendy; Qingfeng Cao | Zendy; Chunjiang Zhou | Zendy; Yao Wang | Zendy; Aize Kijlstra | Zendy; Peizeng Yang | Zendy; Shengping Hou | Zendy

Open Access

Association of Long Noncoding RNAs Polymorphisms With Ankylosing Spondylitis, Vogt-Koyanagi-Harada Disease, and Behcet's Disease

Author(s) -

Yingying Yue,

Jun Zhang,

Yang Lu,

Shengyun Liu,

Jian Qi,

Qingfeng Cao,

Chunjiang Zhou,

Yao Wang,

Aize Kijlstra,

Peizeng Yang,

Shengping Hou

Publication year - 2018

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.17-23247

Subject(s) - vogt–koyanagi–harada disease , single nucleotide polymorphism , ankylosing spondylitis , medicine , behcet's disease , uveitis , immunology , genotype , snp , spondylitis , peripheral blood mononuclear cell , allele , disease , biology , genetics , gene , in vitro

Long noncoding RNAs (lncRNAs) are emerging as important regulators of inflammatory immune responses, whereby genetic variants may affect this biologic function. This study aimed to investigate the association of 110 single nucleotide polymorphisms (SNPs) of lncRNAs, known to be associated with autoimmune disease, in patients with ocular Vogt-Koyanagi-Harada (VKH) disease, Behcet's disease (BD), and acute anterior uveitis (AAU) with or without ankylosing spondylitis (AS).

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