Retinal Pigment Epithelial Cells Control Early Mycobacterium tuberculosis Infection via Interferon Signaling | Zendy

Rina La Distia Nora | Zendy; Kimberley V. Walburg | Zendy; P. Martin van Hagen | Zendy; Sigrid M.A. Swagemakers | Zendy; Peter J. van der Spek | Zendy; Edwin Quinten | Zendy; Michelle Helena van Velthoven | Zendy; Tom H. M. Ottenhoff | Zendy; Willem A. Dik | Zendy; Mariëlle C. Haks | Zendy

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Retinal Pigment Epithelial Cells Control Early Mycobacterium tuberculosis Infection via Interferon Signaling

Author(s) -

Rina La Distia Nora,

Kimberley V. Walburg,

P. Martin van Hagen,

Sigrid M.A. Swagemakers,

Peter J. van der Spek,

Edwin Quinten,

Michelle Helena van Velthoven,

Tom H. M. Ottenhoff,

Willem A. Dik,

Mariëlle C. Haks

Publication year - 2018

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.17-23246

Subject(s) - immune privilege , biology , immunology , immune system , innate immune system , mycobacterium tuberculosis , interferon , macrophage , retinal pigment epithelium , proinflammatory cytokine , cytokine , inflammation , interferon gamma , tuberculosis , medicine , retina , pathology , biochemistry , in vitro , neuroscience

Mycobacterium tuberculosis (Mtb) bacilli have been found in retinal pigment epithelial (RPE) cells from uveitis patients without signs of systemic tuberculosis (TB) infection. RPE cells are important for ocular immune privilege and uveitis development.

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