Open AccessFOXC1 Regulates Expression of Prostaglandin Receptors Leading to an Attenuated Response to Latanoprost
Author(s) -
Lance P. Doucette,
Tim Footz,
Michael A. Walter
Publication year - 2018
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.17-23223
Subject(s) - latanoprost , receptor , prostaglandin , microbiology and biotechnology , chemistry , medicine , biology , ophthalmology , glaucoma
This study examines the effect of FOXC1 on the prostaglandin pathway in order to explore FOXC1's role in the prostaglandin-resistant glaucoma phenotype commonly seen in Axenfeld-Rieger syndrome.
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