Autotaxin–Lysophosphatidic Acid Pathway in Intraocular Pressure Regulation and Glaucoma Subtypes
Author(s) -
Megumi Honjo,
Nozomi Igarashi,
Makoto Kurano,
Yutaka Yatomi,
Koji Igarashi,
Kuniyuki Kano,
Junken Aoki,
Robert N. Weinreb,
Makoto Aihara
Publication year - 2018
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.17-23218
Subject(s) - autotaxin , lysophosphatidic acid , glaucoma , intraocular pressure , ophthalmology , medicine , open angle glaucoma , normal tension glaucoma , receptor
To compare the levels of autotaxin (ATX), lysophosphatidic acid (LPA), and lysophosphatidylcholine (LPC) in the aqueous humor (AH) of healthy control subjects with those of patients with different subtypes of glaucoma, and also to investigate the relationship of the ATX-LPA pathway with IOP and subtype of glaucoma.
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