The Role of 2% Rebamipide Eye Drops Related to Conjunctival Differentiation in Superoxide Dismutase-1 (Sod1) Knockout Mice
Author(s) -
Takashi Kojima,
Cem Şimşek,
Ayako Igarashi,
Kazue Aoki,
Kazunari Higa,
Takahiko Shimizu,
Murat Doğru,
Kazuo Tsubota,
Jun Shimazaki
Publication year - 2018
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.17-23213
Subject(s) - rebamipide , involucrin , conjunctiva , superoxide dismutase , knockout mouse , sod1 , immunohistochemistry , chemistry , tissue transglutaminase , microbiology and biotechnology , pathology , medicine , immunology , keratinocyte , biology , biochemistry , oxidative stress , in vitro , receptor , enzyme
The superoxide dismutase-1 knockout (Sod1-/-) mouse is an age-related dry eye mouse model. We evaluated the role of 2% rebamipide ophthalmic solution on the conjunctiva and ocular surface alterations in Sod1-/- mice.
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