HLA Class I Antigen Expression in Conjunctival Melanoma Is Not Associated With PD-L1/PD-1 Status | Zendy

Jinfeng Cao | Zendy; Niels J. Brouwer | Zendy; Ekaterina S. Jordanova | Zendy; Marina Marinkovic | Zendy; Sjoerd G. van Duinen | Zendy; Nadine E. de Waard | Zendy; Bruce R. Ksander | Zendy; Arend Mulder | Zendy; Frans H.J. Claas | Zendy; Mirjam H.M. Heemskerk | Zendy; Martine J. Jager | Zendy

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HLA Class I Antigen Expression in Conjunctival Melanoma Is Not Associated With PD-L1/PD-1 Status

Author(s) -

Jinfeng Cao,

Niels J. Brouwer,

Ekaterina S. Jordanova,

Marina Marinkovic,

Sjoerd G. van Duinen,

Nadine E. de Waard,

Bruce R. Ksander,

Arend Mulder,

Frans H.J. Claas,

Mirjam H.M. Heemskerk,

Martine J. Jager

Publication year - 2018

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.17-23209

Subject(s) - human leukocyte antigen , medicine , class (philosophy) , immunology , antigen , melanoma , cancer research , computer science , artificial intelligence

Antitumor T cells need expression of HLA class I molecules but can be inhibited by ligands such as programmed death ligand 1 (PD-L1). We determined expression and regulation of these molecules in human conjunctival melanoma (CM) samples, cell lines, and murine xenografts.

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